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Showing posts from August, 2020

Upregulation & Downregulation IRL

Pilots & heroin & voting & endorphins & 2-way streets Bihari thinks naltrexone works by increasing endorphins, I think excess endorphins are often the problem, and the antagonist can sometimes be helpful. —Ray Peat   When pilots test for a license to fly airplanes they have to demonstrate that they can do instrument navigation. Instrument navigation is used when a pilot can’t see the environment he’s flying in, either because it’s nighttime or it’s cloudy.   To do instrument navigation he has to learn to shut off his sensory perception, especially that streaming into the eyes because the sensory field is incomplete for flying safely. Under those circumstances shutting off the senses & trusting only the instruments is not easy to do. There is always risk of confusion & inadvertently reverting to the senses, even when they are sensing incorrectly. In the dark the senses may tell a pilot he’s going down when he’s really going up, or that he’s going up when he’s re